Ras/MAPK Pathway: From Bedside to Bench and Back
نویسندگان
چکیده
Proceedings From the 2009 Genetic Syndromes of the Ras/MAPK Pathway: From Bedside to Bench and Back Katherine A. Rauen,* Lisa Schoyer, Frank McCormick, Angela E. Lin, Judith E. Allanson, David A. Stevenson, Karen W. Gripp, Giovanni Neri, John C. Carey, Eric Legius, Marco Tartaglia, Suzanne Schubbert, Amy E. Roberts, Bruce D. Gelb, Kevin Shannon, David H. Gutmann, Martin McMahon, Carmen Guerra, James A. Fagin, Benjamin Yu, Yoko Aoki, Benjamin G. Neel, Allan Balmain, Richard R. Drake, Garry P. Nolan, Martin Zenker, Gideon Bollag, Judith Sebolt-Leopold, Jackson B. Gibbs, Alcino J. Silva, E. Elizabeth Patton, David H. Viskochil, Mark W. Kieran, Bruce R. Korf, Randi J. Hagerman, Roger J. Packer, and Teri Melese University of California San Francisco, San Francisco, California Costello Syndrome Family Network, Altadena, California MassGen Hospital for Children, Boston, Massachusetts Children’s Hospital Eastern Ontario, Ottawa, Canada University of Utah, Salt Lake City, Utah Alfred I. duPont Hospital for Children, Wilmington, Delaware Universita Cattolica del S. Cuore, Rome, Italy Catholic University Leuven, Leuven, Belgium Istituto Superiore di Sanit a, Rome, Italy
منابع مشابه
Proceedings from the 2009 genetic syndromes of the Ras/MAPK pathway: From bedside to bench and back.
The RASopathies are a group of genetic syndromes caused by germline mutations in genes that encode components of the Ras/mitogen-activated protein kinase (MAPK) pathway. Some of these syndromes are neurofibromatosis type 1, Noonan syndrome, Costello syndrome, cardio-facio-cutaneous syndrome, LEOPARD syndrome and Legius syndrome. Their common underlying pathogenetic mechanism brings about signif...
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تاریخ انتشار 2009